I expect that some modders can try a scenario about the beaver wars.
beggining in 1640 to 1701 with the paix of montreal. For one side the iroquois supplied with firearms by the dutch at fort orange, for the other side the algonquins, hurons, susquehannocks and the french. The first two allied with the french and the susquehannas free of aliances fighting bitterly the iroquois. You can include the eries, the neutrals and at east of the longhouse people, the mahicans and the new england tribes... A scenario where, furs, firearms and a brutal way of war are protagonists. I can help.